Cancer cells may streamline their genomes in order to proliferate more easily


Cancer cells may streamline their genomes in order to proliferate more easily



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22 Comments

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  • What does streamlining genomes mean? what are some obvious implications if such were the case as compared to no streamlining of genomes?

  • albert Einstein said “if you can not explain something simplistically, you don’t understand it yourself.”

  • did not understand one single thing in research paper… please explain in english

  • Why can’t cancer cells use their powers as a force of good, the muggy little devils.

  • Can I get an ELI5 please

  • This should be in r/cancer

  • What a horrible title.

  • cancer cells with further mutated streamlined genomes proliferate more easily

  • Isn’t the title backwards?

    “Cancer cells that proliferate more frequently have streamlined genome” sounds more correct and logical

  • I didn’t even know that cancer cells had gardens. My genomes are just chubby little bearded guys.

  • I thought cancer cells were regular cells that had suffered DNA damage…so being more susceptible to DNA damage doesn’t seem newsworthy.

  • since this is /r/science can this have misleading title flair please

    translated into it into non-click-bait-english, it should read as:

    “having streamlined genomes may allow cancer cells to proliferate more easily”

  • Yeah… I guess Cancer cells are actually cells that are stronger than our own cells… Like… They evolved, we didn’t. Darwinism kicking us in the butt (or lungs, or just choose the place).

  • Can someone ELI5? Or even ELI20? Is this a good thing or a bad thing?

  • This is total non-news. Cancer is, essentially by definition, cells which have accumulated mutations which have conferred the ability to proliferate.

    There are some interesting subtleties, but the title and main conclusion is pure clickbait.

  • Ugh. Why can’t we kill this disease already?!?

  • I wish they would phrase it more correctly as: “Those cells that streamline their genomes proliferate more easily.” I see no reason to phrase it as if a willful action is involved.

  • Would this be the cancer cells going back to there roots as single cellular organisms. As this is what all bacteria/archea do?

  • So there is an elephant in the room called Aneuploidy in this article that isn’t really discussed. A loss of genes like P53 are thought to facilitate this gene instability/somatic mosacism. As far as I’m aware this was thought to be somewhat random, although we’ve known certain proteins under certain conditions to cause semi directed mutations before (high heat with HSP90 in drosophila). I understand that some of this would be out of bounds to speculate on in the journal article, but I would like to think how the researchers fit this with what we already know about Aneuploidy in cancer.

  • Doesn’t “in order to” put the cart before the horse?

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